Subgroup analyses based on study region showed that a slightly significant increased association between history of prostate cancer and ovarian cancer risk was observed in Europe (RR = 1.08, 95% CI = 1.01–1.16, I 2 = 0.00%), but not in America (RR = 1.64, 95% CI = 0.97–2.76) and Asia region (RR = 0.60, 95% CI = 0.03–10.73) (Table 4 ).
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First-degree family history of prostate cancer is associated the risk of breast cancer and ovarian cancer.
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