An association has been detected between biomass smoke exposure and gastric cancer, as well as biomass smoke exposure and urinary 1-hydroxypyrene (1-OHP), a PAH metabolite, with a significant trend for dose in a study from Zambia.
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Wood cookstove use is associated with gastric cancer in Central America and mediated by host genetics.
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The sentences
In the final multivariate model, a highly significant interaction (OR 3.1, 1.2–7.8) was noted between wood cookstove use and the rs1800440 metabolizing genotype, highlighting an important gene-environment interaction.