Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance.

The difference in blood glucose levels (HFD: median = 13.41 mmol/L, IQR = 9.87–15.37 mmol/L; HFDmetf: median = 11.47 mmol/L, IQR = 10.97–13.28 mmol/L; CD: median = 11.34 mmol/L, IQR = 11.06–11.95 mmol/L; CDmetf: median = 9.33 mmol/L, IQR = 9.27–9.67 mmol/L) did not reach statistical significance after adjusting the p -value.

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