Liver X receptors induce antiproliferative effects in basal-like breast cancer.

Mol Oncol · 2023 · PMC10552888 · PMID 37341140

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

borderline significanceP = 0.059so close (0.05 < p ≤ 0.1)

In the basal‐like model (MAS98.12), a dose–response experiment resulted in reduction of tumor growth compared with control at a dose of 40 mg·kg −1 with borderline significance (Wilcoxon's P = 0.059).

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did not reach statistical significanceno p-value reported

However, the difference in protein expression did not reach statistical significance after correction for multiple testing (false discovery rate [FDR]‐adjusted P ‐values).

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of borderline significanceno p-value reported

In our monotherapy experiments, the basal‐like PDX model showed a growth inhibitory response to LXR ligands of borderline significance not apparent in the luminal PDX.

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