Attenuated IL-2 muteins leverage the TCR signal to enhance regulatory T cell homeostasis and response <i>in vivo</i>.

Front Immunol · 2023 · PMC10556740 · PMID 37809101

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showed a trendno p-value reported

The red and purple modules also showed a trend of negative correlation with MHC class II blockade, with the attenuated muteins generating stronger effect compared to WT IL-2.

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