Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies.

Blood Adv · 2023 · PMC10558604 · PMID 37352275

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did not reach statistical significanceno p-value reported

Consequently, some well-established associations, such as the increased sensitivity of the IGHV-unmutated-CLL (U-CLL) group to ibrutinib, 3 , 47 could be detected in monoculture but did not reach statistical significance in coculture ( Figure 4 A; supplemental Table 5 ).

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