a strong trendp = 0.051
In the subset MSSOpoly, differences, most of which were not statistically significant, could be obtained in onset symptoms and symptoms at the last visit, with a strong trend of a higher rate of walking impairments in MSSOpoly (68%) compared to MSS- (50%, p = 0.051). 58% of MSSOpoly were working at the last reported visit compared to 67% in MSS- ( p = 0.4).