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Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation.

Mol Metab · 2023 · PMC10561121 · PMID 37714377

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In female mice, there were also increases in energy expenditure, O 2 consumption, and CO 2 production, but these did not reach statistical significance ( Supplementary Figs. 4A–D ).

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