Proteomics of CKD progression in the chronic renal insufficiency cohort.

Nat Commun · 2023 · PMC10564759 · PMID 37816758

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nominally significantno p-value reported

TWSG1, a protein risk factor also found to be an independent risk factor for CKD progression 20 , with a nominally significant MR association in CKDi25 in our study, is an antagonist of BMP 7, which is produced in the kidney and is protective against renal fibrosis and other types of renal injury in experimental models 21 .

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