HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria.

Flow cytometric analysis of mucosal B-cell subsets also showed a trend toward a decreased frequency of mature naïve (MN) cells, and conversely, an increased frequency of resting memory (RM) B cells in eART as compared to lART (Fig. 1b and Supplementary Fig. 1b–d ) as previously reported 28 .

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Highly significant immunoreactive protein hits ( Z score >5) were comparably detected for both eART- and lART-derived intestinal mAbs (Fig. 2g ).

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