Comparison of SP142 and 22C3 PD-L1 assays in a population-based cohort of triple-negative breast cancer patients in the context of their clinically established scoring algorithms.

Breast Cancer Res · 2023 · PMC10566164 · PMID 37817263

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hedged sentences

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

borderline significantp = 0.051so close (0.05 < p ≤ 0.1)

When using 22C3 CPS ≥ 1 cut-off, NHG was significantly associated with PD-L1 IHC expression ( p = 0.045) and Ki-67 borderline significant ( p = 0.051; Additional file 3 : Table S3).

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did not reach statistical significanceno p-value reported

When using CPS ≥ 10 for 22C3, only medullary features and TIL abundance were significantly associated with PD-L1 status (both p values < 0.001) and the association between PD-L1 and NHG and Ki-67 did not reach statistical significance (Table 2 ).

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