Atopic Dermatitis: Molecular Alterations between Lesional and Non-Lesional Skin Determined Noninvasively by In Vivo Confocal Raman Microspectroscopy.

Although the curves seem to differ from each other in a clear trend, with LAS having a lower concentration of weakly bound water over most of the SC depth, no difference reaches the level of statistical significance.

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The result shows a lower ICL concentration in LAS than nLAS for the superficial and intermediate SC depth (significant for 0–10% and highly significant for 20–70% SC depth, Figure 1 A).

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