Transferrin-Conjugated Melittin-Loaded L-Arginine-Coated Iron Oxide Nanoparticles for Mitigating Beta-Amyloid Pathology of the 5XFAD Mouse Brain.

Notably, CD68 expression also displayed an increasing trend within microglia adjacent to amyloid plaques.

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While the Tf-MeLioNs group displayed elevated protein expression of ACE2 and neprilysin as well, the changes did not reach statistical significance ( Figure 6 C and Figure 6 D, respectively).

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