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Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction.

Nat Commun · 2023 · PMC10575978 · PMID 37833292

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However, the targeted proteomics approach yielded discrete upregulations that did not reach statistical significance in mouse microglia (Supplementary Fig. 6I ), but yielded significant upregulation of ACO2,CS, FH, IDH2, IDH3A and MDH2 (Supplementary Fig. 6J ) in human iMGLs.

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