This analysis showed a slight trend toward a further reduction in both the total and peak ATP release in four VVRIs compared with three VVRIs; overall, there was no statistically significant difference between three and four VVRIs for any RV16 infection state.
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The sentences
Furthermore, when airway epithelial cells are infected with hRV, there is an overall trend towards the reduction in ATP released when cells are treated with VVRIs, either individually or in combination.
Furthermore, when the reduction in ATP as a response to the application of three or four VVRIs was compared directly, there was no significant difference in the extent of ATP released, though four VVRIs showed a trend towards a greater reduction in ATP release.