Intra-host <i>Trypanosoma cruzi</i> strain dynamics shape disease progression: the missing link in Chagas disease pathogenesis.

Interestingly, macaques with progressive disease tended to have had more pronounced body weight loss at the time of infection compared with those with better control of the infection, suggesting a more severe acute phase, although this did not reach statistical significance ( Fig. 2D , P = 0.076).

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