Analysis of Plasma Circulating Tumor DNA in Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Modified FOLFIRINOX: Clinical Relevance of DNA Damage Repair Gene Alteration Detection.

Cancer Res Treat · 2023 · PMC10582539 · PMID 37139665

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showed a trendno p-value reported

We found that the detection of DDR gene ( BRCA1 , BRCA2 , ATM , MLH1 ) mutations in plasma ctDNA at baseline was significantly associated with better PFS and showed a trend toward better OS.

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