Barely Significant
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LncRNA MALAT1/microRNA-30b axis regulates macrophage polarization and function.

Front Immunol · 2023 · PMC10582718 · PMID 37860007

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hedged sentences
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantP<0.001actually significant
To validate this further, we transfected cells with ASO-MALAT1 and miR-30b mimic and observed a highly significant reduction in TLR8 ( P<0.001 ).

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showed a trendno p-value reported
In contrast, the expression of M1Mφ markers iNOS (1.68 ± 0.87-fold), STAT1 (0.87 ± 0.52-fold), TNF-α (1.34 ± 0.49-fold), and ARG2 (1.81 ± 0.73-fold) showed a trend of upregulation in MALAT1 knockdown conditions, albeit the changes were not significant ( Figure 2A ; lower panel).

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