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Association of childhood infections and perinatal factors with ankylosing spondylitis: a Swedish nationwide case-control and sibling study.

RMD Open · 2023 · PMC10582879 · PMID 37845081

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26 27 While we found a point estimate suggesting a protective effect of appendectomy (with or without appendicitis) in AS, it was less pronounced than in previous studies and failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.