Dense granule protein 3 of <i>Toxoplasma gondii</i> plays a crucial role in the capability of the tissue cysts of the parasite to persist in the presence of anti-cyst CD8⁺ T cells during the chronic stage of infection.

In contrast, the cerebral BAG1 mRNA levels of the WT Pru-infected mice at 7 days after the CD8 + T-cell transfer were slightly greater than half of those of the control mice at the time of the T-cell transfer, and the difference did not reach statistical significance ( p = 0.208, Figure 4A ).

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