A potential adverse role for leptin and cardiac leptin receptor in the right ventricle in pulmonary arterial hypertension: effect of metformin is BMPR2 mutation-specific.

Front Med (Lausanne) · 2023 · PMC10586504 · PMID 37869164

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moderately significantno p-value reported

In accordance with prior publications in PAH patients ( 15 , 16 , 21 ), our data also shows an increase in the circulating levels of leptin in PAH patients and a moderately significant correlation with BMI.

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