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Evaluation of the effectiveness of microneedling with tranexamic acid in comparison with microneedling with vitamin C in the treatment of melasma: A prospective and single-blind clinical trial.

Health Sci Rep · 2023 · PMC10588557 · PMID 37867785

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However, it is essential to note that the disparity between these two treatments did not reach statistical significance. 33 TXA, vitamin C, and microneedling have been identified as essential therapeutic interventions for melasma, and the current study's findings are consistent with this assertion.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.