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Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor-modulating factors.

Blood Adv · 2023 · PMC10598500 · PMID 37257194

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Interestingly, in whole blood, only mild secretion could be observed, which did not reach statistical significance, whereas C5a stimulation of isolated platelets resulted in significant CXCL4 secretion ( supplemental Figure 22 B).

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