Risk of major adverse cardiovascular events in patients with rheumatoid arthritis treated with conventional synthetic, biologic and targeted synthetic disease-modifying antirheumatic drugs: observational data from the German RABBIT register.

35 Other stratifications, eg, by history of CVD or smoking and age separately, showed higher estimates, which did not reach statistical significance. 35 36 In our study, we performed several subgroup analyses, especially to explore the impact of individual cardiovascular risk factors.

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