Treatments During Pregnancy Targeting ERBB2 and Outcomes of Pregnant Individuals and Newborns.

JAMA Netw Open · 2023 · PMC10603505 · PMID 37883083

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significanceP = .09so close (0.05 < p ≤ 0.1)

There was an overreporting of cardiovascular malformation (ROR, 4.46 [95% CI, 1.02-19.52]) with trastuzumab-emtansine exposure (n = 20), although the Fisher exact test did not reach statistical significance ( P = .09).

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highly significantno p-value reported

Second, we identified strong, highly significant overreporting of congenital respiratory tract disorders and neonatal kidney failure.

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