Neuroblastoma Interaction with the Tumour Microenvironment and Its Implications for Treatment and Disease Progression.

Curr Oncol · 2023 · PMC10605583 · PMID 37887559

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Finally, the NB tumours as a whole showed a trend for lower infiltration of T cells within the TME (e.g., CD8+ cells) [ 23 ], while macrophages with noninflammatory phenotype (M2) were abundant (assayed by probing for CD163), suggesting an overall immunosuppressive environment [ 23 , 30 , 31 ].

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