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Janus Kinase Inhibitors in Rheumatoid Arthritis: An Update on the Efficacy and Safety of Tofacitinib, Baricitinib and Upadacitinib.

J Clin Med · 2023 · PMC10607454 · PMID 37892827

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Lastly, when attempting to replicate ORAL Surveillance’s over 65 group with cardiovascular risk factors, the sub analysis demonstrated that TOFA treated patients had a numerically higher risk for the primary composite compared to the TNFi treated patients, but this trend did not reach statistical significance with a HR of 1.24 [ 44 ]. 8.

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