Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring.

Pharmaceuticals (Basel) · 2023 · PMC10609883 · PMID 37895954

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did not reach statistical significanceno p-value reported

We observed that treatment with compounds 2a – c resulted only in slight or no reduction in cell viability in LNCAP and PC-3 cells, with the only exception of 2c showing an IC 50 value of 32 μM on LNCAP, although data did not reach statistical significance.

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