The European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany Study (average follow-up = 8 years) indicated that dissatisfaction with life was associated with the elevated risk of stroke in women, while the results in men did not reach statistical significance: HR (95% CI) = 1.69 (1.05, 2.73) and 1.40 (0.89, 2.19), respectively.
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Life satisfaction and the risk of atherosclerotic cardiovascular disease in the general Japanese population: the Suita Study.
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