Clinical and Prognostic Biomarker Value of Blood-Circulating Inflammatory Cytokines in Hepatocellular Carcinoma.

Oncology · 2023 · PMC10614568 · PMID 37467732

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

did not reach statistical significancep = 0.055so close (0.05 < p ≤ 0.1)

Serum IL-22 was elevated in 325 patients, and in these patients, the median OS was 10.71 (95% CI: [8.8, 14.85), which was shorter compared to the OS of 15.74 months (95% CI: 13.17, 17.87) in patients with low IL-22 but did not reach statistical significance ( p = 0.055) ( Table 2 ).

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