According to the latest data, the prevalence of UC was estimated to be 5 million cases around the world, and there is an increasing trend in some emerging industrialized countries ( Le Berre et al., 2023 ; Liu J. et al., 2023 ).
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Puerarin alleviates inflammation and pathological damage in colitis mice by regulating metabolism and gut microbiota.
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However, compared to the UC group, the PUE group reversed the change in F/B ratio and showed a trend toward normalization to that of the control group.