Polymorphisms in Cyclooxygenase, Lipoxygenase, and TP53 Genes Predict Colorectal Polyp Risk Reduction by Aspirin in the seAFOod Polyp Prevention Trial.

Cancer Prev Res (Phila) · 2023 · PMC10618644 · PMID 37756582

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did not reach statistical significanceno p-value reported

All the other PTGS1 , PTGS2 and HPGD SNPs did not reach statistical significance for a difference in total colorectal polyp number between aspirin and placebo users according to genotype (Supplementary Table S2).

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just failed to reach statistical significanceno p-value reported

The reduction in total colorectal polyp number associated with EPA use in the seAFOod trial was modest and just failed to reach statistical significance ( 17–18 ).

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