Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency.

Redox Biol · 2023 · PMC10618796 · PMID 37883842

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0.0550

closest p · 1.1× alpha

0.0550

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showed a trendP = 0.055so close (0.05 < p ≤ 0.1)

Quantification of L-2-hydroxyglutarate showed a trend (P = 0.055) to decrease in the OB of the Ndufs4 KO mouse ( Fig. 2 E), whereas α-ketoglutarate concentration was unchanged ( Fig. 2 F).

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