Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan.

Hum Brain Mapp · 2023 · PMC10619384 · PMID 37800366

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an overall trendno p-value reported

More importantly, the GS topography exhibited an overall trend of spatiotemporal dedifferentiation with age, with dedifferentiation and differentiation tendencies present in both the temporal and spatial dimensions.

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showed a trendno p-value reported

These findings suggest that spatiotemporal dedifferentiation dominates brain aging, although the sensorimotor system showed a trend of temporal differentiation. 3.2.

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