Comparative study in estrogen-depleted mice identifies skeletal and osteocyte transcriptomic responses to abaloparatide and teriparatide.

JCI Insight · 2023 · PMC10619488 · PMID 37870958

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highly significantno p-value reported

Two-way ANOVA showed highly significant effects of both treatments on bone microstructure by μCT and histomorphometry in vertebra trabecular bone ( Supplemental Figures 2 and 3 and Supplemental Table 1 ).

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did not reach statistical significanceno p-value reported

While osteocytes tend to respond to ovariectomy with an enlargement of their lacunae (+8.7%), this difference versus sham controls did not reach statistical significance by 2-way ANOVA.

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