Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease.

PLoS Negl Trop Dis · 2023 · PMC10619880 · PMID 37862368

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0930

boldest claim

The sentences

fell short of significancep = 0.074so close (0.05 < p ≤ 0.1)

Lactoferrin was significantly raised in scarring in the Gambian cohort (p = 0.0074) and was raised but fell short of significance in the Tanzanian cohort (p = 0.074).

also in 60 other papers

fell just short of significancep = 0.093so close (0.05 < p ≤ 0.1)

In samples from those with scarring, lysozyme, IL-10 and CXC chemokines IL-8 and CXCL1 were significantly increased (p = 0.016, 0.046, 0.016, and 0.037 respectively, mixed effects logistic regression) while IP-10 and lactoferrin fell just short of significance (p = 0.093 and 0.074 respectively).

also in 20 other papers

a marked trendno p-value reported

Analysing all timepoints together in an unpaired analysis, there was a marked trend towards higher CXCL1, IL-8, IP-10 and lactoferrin during infection.

also in 109 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.