Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α.

Mol Oncol · 2023 · PMC10620129 · PMID 37584455

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did not reach statistical significanceno p-value reported

Canagliflozin and RT monotherapies reduced tumor growth by 18–26% and 32–44% compared with control mice; however, this did not reach statistical significance at endpoint (Fig. 2B ).

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