Due to the exploratory nature of this analysis, we chose to further analyze all nominally significant DMRs which also pass the post-hoc methylation difference filtering. 1,316 DMRs were identified with a diet-associated methylation change in at least one strain ( Fig 5A and S16 – S18 Tables).
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Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.
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