Use of a ferroptosis-related gene signature to construct diagnostic and prognostic models for assessing immune infiltration in metabolic dysfunction-associated fatty liver disease.

The expression levels of ENO3 , FABP4 , FADS2 , FAT1 , and ITIH3 in the MAFLD dataset showed very highly significant differences among the different groups ( p < 0.001).

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However, the expression levels of ACSL4 , ENO3 , and FNDC5 were negatively correlated with the ESTIMATE and Immune Scores, but this did not reach statistical significance (r < 0, p > 0.05). 3.10 Differential analysis of FRDEG expression in clinical subgroups To explore the difference in the expression levels of the 13 FRDEGs ( ACSL4 , CHAC1 , ENO3 , ENPP2 , FABP4 , FADS2 , FAT1 , FNDC5 , ITIH3 , NR4A1 , SCD , and SQLE ) in the GSE48452 of the MAFLD dataset, we first compiled the clinical information from the 32 samples of the GSE48452 dataset and drew the clinical information table ( Supplementary Table S8 ).

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