Barely Significant
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Intraoperative Radiotherapy as a Tumour-Bed Boost Combined with Whole Breast Irradiation Versus Conventional Radiotherapy in Patients with Early-Stage Breast Cancer: A Systematic Review and Meta-analysis.

Ann Surg Oncol · 2023 · PMC10625949 · PMID 37507556

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showed a trendno p-value reported
The pooled RR for LRR showed no statistically significant difference between the IORT boost+WBI group and the conventional radiotherapy group (RR = 0.77, 95% CI: 0.54–1.09, P = 0.14), but LRR in the IORT boost+WBI group showed a trend towards improvement.

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