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Strategies to combat Gram-negative bacterial resistance to conventional antibacterial drugs: a review.

Osong Public Health Res Perspect · 2023 · PMC10626324 · PMID 37920891

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a clear trendno p-value reported
There is a clear trend towards narrow-spectrum or even pathogen-specific approaches, which require a highly developed diagnostic infrastructure that may not be accessible in developing and underdeveloped nations.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.