The metabolic response of human trophoblasts derived from term placentas to metformin.

Diabetologia · 2023 · PMC10627909 · PMID 37670017

Europe PMC DOI

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0.2300

closest p · 4.6× alpha

0.2300

boldest claim

The sentences

did not reach statistical significancep =0.23not close (p > 0.1)

Pyruvate-supported OXPHOS was lower in trophoblasts treated with 0.1 mmol/l metformin than in trophoblasts treated with vehicle (control) ( p <0.001); the OXPHOS was also lower in trophoblasts treated with 0.01 mmol/l metformin although this did not reach statistical significance ( p =0.23; Fig. 1 a).

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