Glucose uptake into adipose tissue did not differ between PLX5622-treated and control groups, whereas glucose uptake into skeletal muscle was increased in PLX5622-treated mice, yet the difference did not reach statistical significance ( p =0.0519; Fig. 5 e).
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CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice.
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0.0519
0.0519