Combined in vitro/in vivo genome-wide CRISPR screens in triple negative breast cancer identify cancer stemness regulators in paclitaxel resistance.

Oncogenesis · 2023 · PMC10628277 · PMID 37932309

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showed a trendno p-value reported

4C, D , by study endpoint, both HIST1H4A and FRG2 gene silencing significantly (Mann–Whitney U test) increased lung metastatic nodule counts, while the FOXR2 and ATP8B3 KOs both also showed a trend toward increased lung nodules, but not reaching significance.

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