Numerically, the first-line median TTNT appeared to favor patients with stage IVA1 over stage IVA2 (6.0 [95% CI, 5.0-7.6] vs 4.4 [95% CI, 3.6-6.9] months, respectively) but did not reach statistical significance ( P = .2).
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International study of treatment efficacy in SS shows superiority of combination therapy and heterogeneity of treatment strategies.
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