Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave.

It is worth noting that the PCR-positive individuals with a Delta Spike IgG-seroconversion group also had a lower baseline antibody response against Delta Spike than PCR-negative individuals with a Delta Spike IgG-seroconversion, though it did not reach statistical significance.

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