Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Escitalopram Pharmacokinetics: A Cohort Study.

Ther Drug Monit · 2023 · PMC10635340 · PMID 37363832

Europe PMC DOI

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closest p · 1.4× alpha

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showed a trendP = 0.069so close (0.05 < p ≤ 0.1)

The repeated-measures analysis of variance model did not report any significant changes in AUC 0-24 , CL/F, C 0 , t max , t 1/2 and V d /F ( P = 0.39, P = 0.47, P = 0.42, P = 0.23, P = 0.40, and P = 0.12, respectively), but showed a trend for C max ( P = 0.069).

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