Chronic Stress Exacerbates Hyperglycemia-Induced Affective Symptoms in Male Mice.

Neuroimmunomodulation · 2023 · PMC10641805 · PMID 37852199

Europe PMC DOI

hedged sentences

0.0535

closest p · 1.1× alpha

0.0608

boldest claim

The sentences

approached significancep = 0.0535so close (0.05 < p ≤ 0.1)

STZ significantly increased immobility time ( F (1, 45) = 31.39, p < 0.0001, η 2 p = 0.4109), and the effect of UCMS on immobility time approached significance ( F (1, 45) = 3.930, p = 0.0535, η 2 p = 0.0803).

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failed to reach significancep = 0.0608so close (0.05 < p ≤ 0.1)

While the STZ × UCMS × time interaction failed to reach significance ( p = 0.0608), this stress-induced elevation appears more pronounced in STZ mice, indicating that the STZ mice may be more vulnerable to stress-induced perturbations in blood glucose levels.

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trending toward significanceno p-value reported

While a stepwise pattern was observed in FST, such that STZ-UCMS mice showed the highest immobility times, the effect of UCMS on immobility was only trending toward significance.

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