Barely Significant
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Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study.

BMC Med · 2023 · PMC10642059 · PMID 37953258

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However, in line with the RERI analyses, the multiplicative interactions of PPD and inflammation markers were stronger for CVD mortality (HRs ranged from 1.12 to 1.18; extent PPD and fibrinogen: HR = 1.147, P = 0.006; extent PPD and inflammation score: HR = 1.134, P = 0.042) than for all-cause mortality (extent PPD and fibrinogen: HR = 1.075, P = 0.018; extent PPD and inflammation score: HR = 1.069, P = 0.073) and did not reach statistical significance for non-CVD mortality (Additional file 1 : Table S5).

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