A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a bupivacaine hydrochloride implant in patients undergoing abdominoplasty.

Reg Anesth Pain Med · 2023 · PMC10646917 · PMID 37076252

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failed to reach statistical significanceno p-value reported

If a variable failed to reach statistical significance, no subsequent variables would be declared statistically significant.

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failed to reach significanceno p-value reported

Prespecified key secondary outcomes included SPI48 and SPI72, percentage of opioid-free patients through 24, 48, and 72 hours, and adverse events, which were tested sequentially to control for multiplicity (ie, if the first variable failed to reach significance, no subsequent variables were declared statistically significant).

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